Wei Laboratories, Inc.
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What is is Kidney Failure?
Acute kidney failure is the sudden loss of your kidneys' ability to perform their main function of eliminating excess fluid
and salts (electrolytes) as well as waste material from your blood. When your kidneys lose their filtering ability,
dangerous levels of fluid, electrolytes and wastes accumulate in your body.

Acute kidney failure, which is also called acute kidney injury, develops rapidly over a few hours or a few days. Acute
kidney failure is most common in people who are already hospitalized, particularly in critically ill people who need
intensive care.

Acute kidney failure can be fatal and requires intensive treatment. However, acute kidney failure may be reversible. If
you're otherwise in good health, you may recover normal kidney function.

Chronic kidney failure describes the gradual loss of kidney function. In the early stages of chronic kidney failure, you
may have few signs or symptoms. Chronic kidney failure may not become apparent until your kidney function is
significantly impaired. Chronic kidney failure can progress to end-stage kidney disease, which is fatal without artificial
filtering (dialysis) or a kidney transplant.

Symptoms
Signs and symptoms of acute kidney failure may include:
•        Decreased urine output, although occasionally urine output remains normal
•        Fluid retention, causing swelling in your legs, ankles or feet
•        Drowsiness
•        Shortness of breath
•        Fatigue
•        Confusion
•        Nausea
•        Seizures or coma in severe cases
•        Chest pain or pressure

Sometimes acute kidney failure causes no signs or symptoms and is detected through laboratory tests done for
another reason.

Diseases and conditions that commonly cause chronic kidney failure include:
•        Type I diabetes
•        Type II diabetes
•        High blood pressure
•        Enlarged prostate
•        Kidney stones
•        Bladder cancer
•        Kidney cancer
•        A condition that causes urine to back up into your kidneys (vesicoureteral reflux)
•        Polycystic kidney disease
•        Kidney infection (pyelonephritis)
•        Glomerulonephritis
•        Lupus
•        Scleroderma
•        Vasculitis
•        Damage to the artery that carries blood to your kidneys (renal artery stenosis)

Signs and symptoms of kidney failure develop slowly over time if kidney damage progresses slowly. Signs and
symptoms of kidney failure may include:
•        Decreased urine output or no urine output
•        Nausea
•        Vomiting
•        Loss of appetite
•        Fatigue and weakness
•        Sleep problems
•        Decreased mental sharpness
•        Muscle twitches and cramps
•        Swelling of the feet and ankles
•        Persistent itching

Signs and symptoms of kidney failure are often nonspecific, meaning they can also be attributed to other illnesses. In
addition, because your kidneys are highly adaptable and able to compensate for lost function, signs and symptoms of
kidney failure may not appear until irreversible damage has occurred.

Causes
Acute kidney failure occurs when your kidneys suddenly become unable to filter wastes from your blood. Acute kidney
failure can occur when something damages your kidneys, or it can occur when another condition slows blood flow to
your kidneys. Acute kidney failure can also occur when the wastes filtered by your kidneys aren't able to leave your body
through your urine.

Diseases and conditions that may slow blood flow to the kidneys and can lead to kidney failure include:
•        Blood loss
•        Blood pressure medications
•        Heart attack
•        Heart disease
•        Infection
•        Liver cirrhosis
•        Nonsteroidal anti-inflammatory drugs, such as aspirin, ibuprofen and naproxen
•        Severe allergic reaction (anaphylaxis)
•        Severe burns
•        Severe dehydration

Diseases and conditions that damage the kidneys and may lead to acute kidney failure include:
•        Blood clots in the veins and arteries in and around the kidneys
•        Cholesterol deposits that block blood flow in the kidneys
•        Glomerulonephritis
•        Hemolytic uremic syndrome
•        Infection
•        Lupus
•        Medications, such as certain chemotherapy drugs, antibiotics and dyes used during imaging tests
•        Multiple myeloma
•        Scleroderma
•        Thrombotic thrombocytopenic purpura
•        Toxins, such as alcohol, heavy metals and cocaine
•        Vasculitis

Diseases and conditions that block the passage of urine out of the body (urinary obstructions) and can lead to acute
kidney failure include:
•        Bladder cancer
•        Blood clots in the urinary tract
•        Cervical cancer
•        Colon cancer
•        Enlarged prostate
•        Kidney stones
•        Nerve damage involving the nerves that control the bladder
•        Prostate cancer

Western Medicine Treatment
Treatment for acute kidney failure typically requires a hospital stay. Most people with acute kidney failure are already
hospitalized. How long you'll stay in the hospital depends on the reason for your acute kidney failure and how quickly
your kidneys recover.
    o        Treating the underlying cause of your kidney failure
    Treating complications until your kidneys recover
    o        Treatments to balance the amount of fluids in your blood.
    o        Medications to control blood potassium.
    o        Medications to restore blood calcium levels
    o        Dialysis to remove toxins from your blood

Chronic kidney failure has no cure, but treatment can help control signs and symptoms, reduce complications, and
slow the progress of the disease. If your kidneys become severely damaged, you may need treatments for end-stage
kidney disease.
•        Treating complications of kidney failure
•        Treatment to control high blood pressure
•        Medications to lower cholesterol levels. Medications to relieve anemia
•        Medications to relieve swelling
•        Medications to protect your bones
•        A low-protein diet to minimize waste products in your blood

Treatment for end-stage kidney disease
•        Dialysis
•        Kidney transplant.

Alternative Medicine
There is a significant progress using alternative medicine in this area.
If you want a referral of an expert alternative medicine practitioner in your
local area, please use our free referral service by calling our toll-free at
1-888-919-1188, or e-mail us to wei@weilab.com, or click the button
at the right to have us contact you.

Information gathered from the Mayo Clinic
Referral Service for Patients with Kidney Failure
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