Wei Laboratories, Inc.
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What is Fatty Liver?
Fatty liver, also known as fatty liver disease (FLD), is a reversible condition where large vacuoles of triglyceride fat
accumulate in liver cells via the process of steatosis (i.e. abnormal retention of lipids within a cell). Despite having
multiple causes, fatty liver can be considered a single disease that occurs worldwide in those with excessive alcohol
intake and those who are obese (with or without effects of insulin resistance). The condition is also associated with
other diseases that influence fat metabolism. Morphologically it is difficult to distinguish alcoholic FLD from non
alcoholic FLD and both show micro-vesicular and macrovesicular fatty changes at different stages.

Accumulation of fat may also be accompanied by a progressive inflammation of the liver (hepatitis), called
steatohepatitis. By considering the contribution by alcohol, fatty liver may be termed alcoholic steatosis or non-alcoholic
fatty liver disease (NAFLD), and the more severe forms as alcoholic steatohepatitis (part of alcoholic liver disease) and
non-alcoholic steatohepatitis (NASH).

Symptoms
Most individuals are asymptomatic and are usually discovered incidentally because of abnormal liver function tests or
hepatomegaly noted in unrelated medical condition.

Causes
Fatty liver is commonly associated with alcohol or metabolic syndrome (diabetes, hypertension, obesity and
dyslipidemia) but can also be due to any one of many causes.
•        Metabolic
     Abetalipoproteinemia, glycogen storage diseases, Weber-Christian disease, Wolman disease, acute fatty liver of
     pregnancy, lipodystrophy
•        Nutritional
     Malnutrition, total parenteral nutrition, severe weight loss, refeeding syndrome, jejuno-ileal bypass, gastric bypass,
     jejunal diverticulosis with bacterial overgrowth
•        Drugs and toxins
     Amiodarone, methotrexate, diltiazem, highly active antiretroviral therapy, glucocorticoids, tamoxifen, environmental
     hepatotoxins (e.g., phosphorus, mushroom poisoning)
•        Other
     Inflammatory bowel disease, HIV, Hepatitis C especially genotype 3, and Alpha 1-antitrypsin deficiency

Western Medicine Treatment
The treatment of fatty liver depends on what is causing it, and generally, treating the underlying cause will reverse the
process of steatosis if implemented at early stage.

Alternative Medicine
There is a significant progress using alternative medicine in this area.
If you want a referral of an expert alternative medicine practitioner in your
local area, please use our free referral service by calling our toll-free at
1-888-919-1188, or e-mail us to wei@weilab.com, or click the button
at the right to have us contact you.

Information gathered from Wikipedia.com
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